Thankfully, I haven't had any of those happen to me. I think the closest was there was almost an open invite for a dinner, but it was planned to be large in the first place; it was the engagement of two friends of mine.
Back when I could drink at conventions (I can't drink alcohol any more due to my diabetes and stroke), I would sometimes drink a ton of booze, but it'd usually be on the last night, and at a Dead Dog Party (especially true when I was still part of the staff for Megaplex), but I've never drank so much I blacked out, and I've never had a hangover. Go go hydration powers!
For the first one, it's been less "I get sick and have to miss the entire convention" and more "work is a jerk and won't give me the time off for that convention for whatever reason".
Thankfully, I haven't had any of those happen to me. I think the closest was there was almost an