Not a big reality shift. A doctor will never tell you that a a kid under 6 year old with ... bladder problems is not healthy, simply because sometimes it's how much time it takes for the bladder to be a proper one. It's just kinda late.
A good number of babyfurs/diaperfurs (therefore, infantilists) had bed wetting problems or incontinence related problems if not worse (and if it actually stopped), and were forced to use diapers ... and began to like them. Many babyfurs have their fursonas wearing diapers at late age, and even if I cannot confirm that they were all wearing them at this age IRL, allow me to tell you that it's probably not a coincidence ;)
http://www.livestrong.com/article/516874-should-a-5-year-old-wear-a-diaper-at-night/ Not a big real